Biological activity and chemical characterization of ethanol extract from the leaf of Sphagneticola trilobata

Abstract

The study’s objective was to examine the antimicrobial activity of Sphagneticola trilobata opposition to therapeutically separated from human hazardous pathogens and to define its morphological characteristics. The extract was tested for its photochemical substance that was identified by Gas Chromatography-Mass Spectroscopy. The ethanolic extract's working properties were examined using FT-IR. In addition, the extract of ethanol demonstrated antibacterial activity against eight of the ten pathogens examined. At the maximum dose (100 g/ml), the ethanolic extract inhibited S.paratyphi with a maximal zone of 18 mm. The ethanolic extract had MIC values of 100, 80, 60, and 100 μg/ml against bacteria’s including K.oxytoca, V.cholerae, S.typhi, S. paratyphi, S.aureus , E.coli, and P. mirabilis. The MBC values of the ethanolic extract against bacterial pathogens demonstrated 80, 100, 100, 80, 60, 60, 40 and 60 μg/ml. S.trilobata's effective bacterial inhibition rate shows that it could be used as an antibiotic.