LC- HRMS and Phytochemicals Analysis of Gnidia glauca L. leaf crude extract with different solvents

Abstract

The member of the Thymelaeaceae family, Gnidia glauca (Fresen) Gilg, has been found to possess a multitude of traditional phytomedicinal and agrochemical applications. When viewed in its entirety, Gnidia glauca L. (Thymelaeaceae) stands as the most extensive genus within the family, boasting a remarkable 140 to 160 species scattered across Africa, Arabia, India, Madagascar, and Sri Lanka. The leaves of Gnidia glauca L., which are meticulously extracted using chloroform, methanol, and alcohol, yield a diverse array of chemically intricate and biologically potent substances. A staggering number of over 90 compounds have been successfully identified within it. The meticulous phytochemical analysis of Gnidia glauca leaves has revealed the presence of alkaloids, phenols, flavonoids, tannins, glycosides, saponins, terpenoids, and steroids. The objective of this endeavor is to employ LC-HRMS-based techniques to meticulously analyze and detect both targeted and non-targeted phenolic compounds derived from the leaves of Gnidia glauca L.