CNT based high-κ dielectric Ion Sensitive Field Effect Transistor Based Cholesterol Biosensor

Authors

  • Gaurav Keshwani Department of Electronics and Communication Engg. Tezpur University, Tezpur - 784028, Assam, India
  • Jiten Chandra Dutta Department of Electronics and Communication Engg. Tezpur University, Tezpur - 784028, Assam, India

DOI:

https://doi.org/10.5530/ctbp.2021.2.20

Keywords:

CNT, PEI, nanocomposite, cholesterol oxidase, biosensor

Abstract

Carbon nanotube (CNT) based high-κ dielectric ion sensitive field effect transistor (ISFET) based cholesterol biosensor has been realized using Polyethylenimine (PEI) doped CNT channel and nanocomposite of potassium doped CNT with polypyrrole as sensing membrane.Device has been fabricated using solution method and electrical characterization of the device has been carried out after immobilization of enzyme cholesterol oxidase (ChOx) in presence of PBS solution.Device has shown a wide dynamic range (0.5 to 25mM), a good sensitivity of 60 mV/ decade,low response time (~1 s), low detection limit (0.23 mM), good stability (7 months) and high selectivity (interference ~1.8 %).

Schematic diagram of cholesterol ENFET

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Published

2021-05-31

How to Cite

Keshwani, G., & Dutta, J. C. (2021). CNT based high-κ dielectric Ion Sensitive Field Effect Transistor Based Cholesterol Biosensor. Current Trends in Biotechnology and Pharmacy, 15(2), 182–188. https://doi.org/10.5530/ctbp.2021.2.20