Unlocking the Therapeutic Potential of Syzygium cumini Seeds Extract

Order of Publishing in Issue: 
5
Volume :14
Issue :4
October, 2020 - December, 2020
Page No: 
403-414
Authors: 
Utharalakshmi. N, Gayathri. S, Hansika. S, Narendrakumar. G*
Address: 
Department of Biotechnology, School of Bio and Chemical Engineering Sathyabama Institute of Science and technology, Chennai – 600 119, Tamil Nadu, India
Email-ID: 
gnaren22@gmail.com

Abstract
This work provided initial evidence that the methanol and ethanol extract of Syzygium cumini seeds polyphenol compounds are separated. The major polyphenolic compounds are determined and its derivatives posses strong amylase and tryosinase inhibitory activities with IC50 values more than 50μg/ml for amylase and more than 80μg/ml for tryosinase respectively. Such half maximal inhibitory concentration (IC50) values substantiate to manage diabetes and neuroprotective effects in patients to minimize the secondary complications associated with diabetes and melanogenesis.

Keywords: 
Syzygium cumini, Tyrosinase, Amylase activity, Anti-diabetic.
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