A Review on Chloro Substituted Marine Natural Product, Chemical Examination and Biological Activity.

Order of Publishing in Issue: 
10
Volume :13
Issue :1
January, 2019 - March, 2019
Page No: 
72-82
Authors: 
Lakshmi Srinivasa Rao Kundeti, Sharada Ambati, G. Sowmya Srividya, Jhillu Singh Yadav, Nagaiah Kommu
Address: 
Centre for Natural Products and Traditional Knowledge, CSIR-Indian Institute of Chemical Technology, Tarnaka, Hyderabad-500007, Telangana, India
Email-ID: 
nagaiah@iict.res.in

The present review describes the marine chlorosubstituted natural products and their pharmacological properties viz. biological activity, anti-bacterial, antitumor, anti-parasitic, anti-fungal, anti-viral, anti-inflammatory, antioxidant and enzymatic activity. Typical methods of isolation of marine compounds are applied by extensive chromatographic techniques to isolate these compounds which yield in milligram quantities. Further the characterization and structure determination involves spectrometric techniques like FT-IR, H1-NMR, C13-NMR, NOE, HMBC and etc. Although biological activity is assessed for most compounds by extracts a practical drug or lead molecule is yet emerge.

Keywords: 
Nil
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