Principles and Applications of Capillary Electrophoresis in New Drug Discovery

Order of Publishing in Issue: 
14
Volume :2
Issue :1
January, 2008 - March, 2008
Page No: 
142-155
Authors: 
Marothu Vamsi Krishna*, Muppalaneni Srinath and Dannana Gowri Sankar
Address: 
University College of Pharmaceutical Sciences Andhra University, Visakhapatnam-530003, A.P., India

Abstract: This review article focuses on the use of capillary electrophoresis (CE) techniques for performinghigh throughput drug discovery and development applications. The various examples using CE systems for performing physicochemicalprofiling, chiral separations, enzyme and inhibitor activity screening, metabolomic analysis, immunoassay, protein analysis and genetic analysiswere presented.

Keywords: 
Capillary electrophoresis, New drug discovery, Applications
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