Phytoconstituents from the Leaves of Adenanthera Pavonina Linn And Erythrina variegata L. (Syn.= Erythrina indica Lam)

Order of Publishing in Issue: 
1
Volume :10
Issue :1
January, 2016
Page No: 
29-36
Authors: 
Md. Mujahid, Md. Azizur Rahman*, Hefazat H. Siddiqui, Arshad Hussain, Vaseem Ahamad Ansari and Mohammad Irfan Khan
Address: 
Bioactive Research Laboratory, Department of Pharmacy, Integral University, Lucknow, Uttar Pradesh 226026 (India).

Adenanthera pavonina Linn and Erythrina variegata Lam are being used in the Indian traditional systems of medicine for the cure of variety of ailments. Present study was designed to isolate and characterize phytoconstituents from the leaves of A. pavonina Linn and E. variegata Lam. Methanolic extracts of the leaves of A. pavonina and E. variegata were prepared and slurry on silica gel was prepared from these extracts separately. Silica gel was packed in chromatography column and dried slurry was loaded. The column was eluted successively with different solvents in the order of increasing polarity. Chromatographically identical fractions were combined together and concentrated. Isolated phytoconstituents were crystallized and characterized by UV, IR, 1HNMR, 13C-NMR and MS spectroscopy. Isolated phytoconstituents 1, 2, 3 and 4 were characterized as n-tricosanol, α-D-glucopyranosyl- (2→1’)-α-D-glucopyranosyl-(6’→2’ 2 )-α-Dglucopyranosyl-( 6”→1’ 2 →2)-α-D-glucopyranoside, hexatetracontan-1-ol and n-octanyl-1β-Dglucopyranosyl-( 6”→ 1’)-β-D-glucopyranoside respectively. From the present study, it can be concluded that the existing knowledge concerning the phytoconstituents from the leaves of A. pavonina and E. variegata may be enlarged by the current phytoconstituents investigation which is valuable as these drugs are being used in the Indian traditional systems of medicine.

Keywords: 
Adenanthera pavonina, Erythrina variegata, isolation, phytoconstituent, column chromatography
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