Phytochemical and Antimicrobial Studies on the Seeds of Mucuna Monosperma DC

Order of Publishing in Issue: 
9
Volume :2
Issue :2
July, 2008
Page No: 
442-446
Authors: 
G.K. Mallaiah1, K.Thirupathi1, S. Ganapaty2, P. Tirumala Rao3 G. Krishna Mohan*1
Address: 
Department of Pharmacognosy and Centre for Ethnopharmacology, University College of Pharmaceutical Sciences, Kakatiya University, Warangal, India
Address: 
University College of Pharmaceutical Sciences, Andhra University, Waltiar, India
Address: 
Rajah RSRKRR College, Bobbili, Vijaya nagaram, Andhra University, India

The phytochemical study of the seeds of Mucuna monosperma DC. revealed the presenceof flavonoids, sterols, triterpenoids. The separated compounds were identified based ontheir melting points, IR, 1H NMR and mass spectral data, such compounds were acacetin,luteolin, b-sitosterol, stigmasterol, ursolic acid and betulinic acid. The antimicrobial activity ofchloroform and methanolic extract of seed powder was investigated. The methanolic extractexhibited marked antibacterial activity against gram positive, gram negative organisms andfungi.

Keywords: 
Mucuna monosperma, flavonoids, triterpenoids, antimicrobial activity
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