Pemphigus vegetans: A Rare Case Report

Order of Publishing in Issue: 
5
Volume :14
Issue :1
January, 2020 - March, 2020
Page No: 
48-50
Authors: 
Inamdar SZ*[1], Pradeep R[1], Akhila M[1], Jangond A[2], Pradeepthi K[1], Kulkarni RV[1]
Address: 
[1]Department of Pharmacy Practice, BLDEA’s SSM College of Pharmacy and Research Centre, Vijayapur – 586103
Address: 
[2]Department of Dermatology, Shri B.M.Patil Medical College, Hospital & Research Centre, BLDE (Deemed to be University), Vijayapur-586103

Pemphigus vegetans is a rare vesiculobullous autoimmune disease which is a rare variant of pemphigus vulgaris characterized by vegetating plaques in the flexures and lesions in the oral cavity. It is a less common disease and involves the mucosa and skin due to disintegration of cellular adherence (acantholysis) resulting in intradermal split. The lesions are usually painful and if untreated it may be fatal. A 68 years old male patient was admitted with complaints of fluid filled skin lesions over trunk since 3 months. The lesions later ruptured spontaneously and healed with crusting. The lesions gradually progressed to involve axilla, scalp and extremities with no itching. Successful implementation of dexamethasone –cyclophosphamide –pulse (DCP) therapy along with other adjuvant drugs has induced disease remission.

Keywords: 
Pemphigus vegetans, Autoimmune disease, Acantholysis.
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