Isolation of secondary products from Ipomoea digitata – a medicinally important plant

Order of Publishing in Issue: 
3
Volume :4
Issue :2
April, 2010 - June, 2010
Page No: 
660-664
Authors: 
D. Madhavi [1], B. Rama Rao [2], Peddolla Sreenivas [3], G.L. David Krupadanam [3], P. Maheshwari Rao [1], K. Janardhan Reddy [4] and P.B. Kavi Kishor [1]*
Address: 
[1] Department of Genetics, Osmania University, Hyderabad - 500 007, India
Address: 
[2] Natural Products Lab, Indian Institute of Chemical Technology, Hyderabad 500 007, India
Address: 
[3] Department of Chemistry, Osmania University, Hyderabad- 500 007, India
Address: 
[4] Department of Botany, Osmania University, Hyderabad - 500 007, India
Email-ID: 
pbkavi@yahoo.com

Abstract : The paper reports the isolation and characterization of ?-sitosterol, t-cinnamic acid [undecyl (E)-3-(4- hydroxyphenyl)-2-propenoate], an unknown coumarin and a lignan type resin glycoside from the tuberous roots of Ipomoea digitata. The structures of the compounds were elucidated on the basis of extensive chemical and spectroscopic data. Importantly, one of the compounds exhibited significant antibacterial activity against Pseudomonas aeruginosa and E coli. The resin glycosides are known as purgative ingredients and hence have medicinal value. However, the exact chemical and biological activity of the resin glycoside isolated in this study is yet to be ascertained.

Keywords: 
Ipomoea digitata, Convolvulaceae, Undcyl (E)-3-(4-hydroxyhenyl)-2-propenoate, Coumarin, Resin glycoside
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