Inflammation Induced Obesity Associated Diseases: A Mini Review

Order of Publishing in Issue: 
11
Volume :13
Issue :4
October, 2019 - December, 2019
Page No: 
448-460
Authors: 
G.V. Swarnalatha,* R. Senthilkumar
Address: 
Department of Biochemistry, Rayalaseema University, Kurnool, AP, India
Email-ID: 
senthilanal@yahoo.com

A variety of factors including pathogens, damaged cells and other toxic compounds can influence the immune system and this biological response is known as Inflammation. These factors may induce acute and/or chronic inflammatory responses in the heart, pancreas, liver, kidney, lung, brain, intestinal tract and reproductive system, potentially leading to tissue damage or disease. Inflammation is divided into two different formats: Acute and chronic inflammation. Acute inflammation that occurs over seconds, minutes, hours and days following the injury of tissues. The damage will be purely physical or it may involve the activation of an immune response. Chronic inflammation that occurs longer times, days and months. Inflammation is involved in impairment of energy balance as well as insulin resistance and heart diseases. Accumulation of fat in the body causes optimal status of human body health and the stage is known as obesity. Obesity damages several signalling pathways in the body and causes diabetes, some cancers, gall bladder diseases and gall stones, osteoarthritis, gout and breathing problems and asthma. In this minireview, we discuss the inflammation mediated obesity associated diseases.

Keywords: 
Inflammation, Adipocytes, Obesity, Diabetes, Cancer
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