Vaccine Diplomacy: Exploring the Benefits of International Collaboration

Order of Publishing in Issue: 
12
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
110-114
Authors: 
SK Varshney[1], N K Prasanna[2]
Address: 
[1]Department of Science and Technology, New Delhi, India.
Address: 
[2]CSIR-National Institute of Science Communication and Information Resources, New Delhi, India.

Global health diplomacy has given birth to vaccine diplomacy and later it got linked with vaccine science diplomacy which itself an amalgamation of science diplomacy. Since India is leader in vaccine manufacturing, it contributes approximately 60% of vaccines to the global vaccine supply. According to the present scenario, India is harnessing the power of soft skill by offering COVID?19 vaccines to its immediate neighbors to leverage diplomacy.

Keywords: 
Influenza, Vaccine, Pandemic, Antipoverty vaccine, Ascariasis and Trichuriasis,

Academic Output in Smart Agriculture with Conservation of Natural Resources : Indian vs. Global Scenario

Order of Publishing in Issue: 
11
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
101-109
Authors: 
NK Prasanna Kumari[1], RS Jayasomu[1], M Verma[2]
Address: 
[1]Academy of Scientific and Innovative Research, New Delhi, India.
Address: 
[2]Central Sanskrit University, Puri, Odisha, India.

Agriculture is the source of GDP for any country. Effort is being made to analyze the trend of contributors at India and global with identification of major/top research areas, publishing journals, fund sources, organizations, researchers; group authors and cited papers in the index databases of Clarivate Analytics from 2014-2019. India is leading globally in the area of smart agricultural, more paper published in the stream of computer science and engineering.

Keywords: 
Smart agriculture, Mitigation, Biotic Stress, Abiotic stress, Conservation, Natural resources, Biodiversity.

Zirconium Alginate Beads: A Renewable Source for the Biosorption of Fluoride from Contaminated Ground Water

Order of Publishing in Issue: 
8
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
70-78
Authors: 
Aruna Jyothi Kora[1,2]
Address: 
[1]National Centre for Compositional Characterisation of Materials (NCCCM) Bhabha Atomic Research Centre (BARC), ECIL PO, Hyderabad-500062, India. [2]Homi Bhabha National Institute (HBNI), Anushakti Nagar, Mumbai-400 094, India
Email-ID: 
koramaganti@gmail.com

In view of the fluoride induced toxic effects on human health; an effective and simple biosorption method was developed for fluoride laden groundwater using zirconium alginate beads. The various parameters affecting the batch adsorption in fluoride spiked groundwater such as initial fluoride concentration (2.5-10 mg/L), residence time (10-120 min) and pH (5, 7, 9) were studied. The fluoride concentration in the solutions was measured by spectrophotometry at 550 nm using in-house developed zirconyl-xylenol orange complex reagent.

Keywords: 
Alginate, Bioremediation, Biosorption, Fluoride, Groundwater, Zirconium.

Holy Basil: A Potential Herbal Source for Therapeutic Applications

Order of Publishing in Issue: 
10
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
87-100
Authors: 
Lomada Dakshayani[1,#], Neha Merchant[2,#], Sugavasi Smitha[3,#], Gulla Surendra[4], Tamatam Guruprasanth Reddy[4], Dudyala Mamatha[4], Goddumarri Deepthi[4], Dasari Venkata Ramana[4], Thummala Chandrasekhar[5,*], Madhava C Reddy[4,*]
Address: 
[1]Department of Genetics & Genomics, Yogi Vemana University, Kadapa, A.P. 516005, India
Address: 
[2]Department of Bioscience and Biotechnology, Banasthali University, Vanasthali, Rajasthan, 304022, India
Address: 
[3]Department of Sericulture, S.T.S.N. Government Degree College, Kadiri, Ananathapuramu Dt. A.P. India
Address: 
[4]Department of Biotechnology and Bioinformatics, Yogi Vemana University, Kadapa, A.P. 516005, India
Address: 
[5]Department of Environmental Science, Yogi Vemana University, Kadapa, A.P. 516005, India.
Email-ID: 
tcsbiotech@gmail.com

Human dependence on plants, especially for medicinal purpose can be dated back to centuries and this reliance continues till date for various reasons such as minimal cost and easy availability in nature. Ocimum sanctum, commonly known as ‘Holy basil’ is a sacred plant with immense medicinal significance. The present review aims to summarize the holy basil research works and its therapeutic potentials.

Keywords: 
Holy basil, Anti-inflammatory, Anticancer, Anti-diabetic, Anti-oxidant, Anti-microbial.

In vivo Cardioprotective Effect of a Polysaccharide from Lycium europaeum on Cisplatin-induced Heart Injury in Mice

Order of Publishing in Issue: 
9
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
79-86
Authors: 
Ilhem Rjeibi*, Anouar Feriani and Najla Hfaiedh
Address: 
Research unit of Macromolecular Biochemistry and Genetics, Faculty of Sciences of Gafsa, 2112. Gafsa, Tunisia.
Email-ID: 
rjeibii@yahoo.fr

In this study, we aimed to investigate the possible cardioprotective effect of a water-soluble polysaccharide (LEP) from the leaves of Lycium europaeum against cisplatin (CP)-induced heart injury in mice model.

Keywords: 
Lycium europaeum, Cisplatin, Cardioprotective, Polysaccharide, Heart injury.

Formulation and Evaluation of Amoxicillin Trihydrate Orallozenges for Treating Upper Respiratory Tract Infections

Order of Publishing in Issue: 
7
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
62-69
Authors: 
S.Vidyadhara, RLC. Sasidhar, B. Sowjanya Lakshmi, Manisha Lal, P.Nithin
Address: 
Chebrolu Hanumaiah Institute of Pharmaceutical Sciences Chandramoulipuram, Chowdavaram, Guntur, A.P., India.
Email-ID: 
svidyadhara@gmail.com

In the present investigation an attempt has been made to develop Amoxicillin Trihydrate oral lozenges in treatment of upper respiratory tract infection. The lozenges were formulated by soft lozenges method employing Amoxicillin Trihydrate alone and in combination with natural antiseptic ingredients. The lozenges were prepared employing PEG 4000 as matrix base, Stevia (natural sweetener), Acacia (polymer), MCC (disintegrate) other excipients.

Keywords: 
Amoxicillin Trihydrate, Ginger, Tulsi, PEG 4000, MCC, Stevia.

Development and Validation of Stability Indicating RP-HPLC Method for Quantitative Estimation of Levofloxacin Injection 5mg/ml Dosage Form

Order of Publishing in Issue: 
6
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
51-61
Authors: 
N. Prasad Babu[1,*] , Dr. D. Ramachandran[2], K. Geetha Bhavani[3]
Address: 
[1]Department of Chemistry, V.S.R Government Degree & P.G. College, Movva, Andhra Pradesh, India
Address: 
[2]Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur, A.P., India
Address: 
[3]Department of Chemistry, JMJ College for Women, Tenali, Guntur, Andhra Pradesh, India

A new analytical “reverse phase high performance liquid Chromatography (RP-HPLC) assay method has been developed for estimation of” Levofloxacin in injection phase. The separation was achieved by using column Inertsil ODS-3V (250 x 4.6mm, 5μm) mobile phase consisted of 0.05 M solution of citric acid monohydrate and 10 ml of 1.0 M ammonium acetate buffer and acetonitrile in the ratio of (85:15 v/v) . The flow rate was 1.0mL.min-1. Levofloxacin was detected using UV detector at the wavelength of 293 nm.

Keywords: 
RP-HPLC, Levofloxacin, Forced degradation and Validation.

Assessment of Eco-genotoxic Effects of Pesticide Mixtures on Freshwater Fish, Catla catla

Order of Publishing in Issue: 
5
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
44-50
Authors: 
B. Reddi Bhargavi[1], Ravi Kumar Vellanki[2], Rajanikanth Akurathi[1] and Jagadeeswara Reddy Kanala[1,*]
Address: 
[1]Sugen Life Sciences Pvt. Ltd., Tirupati - 517505, AP, India
Address: 
[2]Department of Biotechnology, Vignan University, Vadlamudi, Guntur-522213, AP, India
Email-ID: 
kjreddy32@gmail.com

Eco-genotoxicity was evaluated in fresh water fish, Catla catla using two commercially available pesticide mixtures, viz., Deltamethrin 1% + Triazophos 35% EC and Profenofos 40% EC + Cypermethrin 4% EC. Acute toxicity studies were conducted primarily to determine LC50 of each pesticide mixture. The fish were exposed to each pesticide mixture for 21 days at a dose value of 1/ 20th and 1/10th of LC50. The gills were isolated from the fish at the end of the exposure period, and processed for comet assay.

Keywords: 
Eco-genotoxicity, Acute toxicity, Comet assay, DNA damage.

The Assessment of the Free Radical Scavenging Activity and Flavonoid Contents of Selected Medicinal Plants of Mizoram

Order of Publishing in Issue: 
4
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
34-43
Authors: 
Alex Zohmachhuana[1], Malsawmdawngliana[2], K. Lalrinzuali[3], F. Lalnunmawia[1], M. Vabeiryureilai[3,*], N. Senthil Kumar[4]
Address: 
[1]Dept. of Botany, [2]Dept. of HAMP, [3]Dept. of Zoology, [4]Dept. of Biotechnology Mizoram University, Aizawl - 796004, Mizoram, India.

Herbal medicine has proven to be one of the most well-known fields of traditional medicine worldwide. Extracts from different traditional medicinal plants have been screened to discover the source of therapeutic effects and nature has been a source of medicinal agent for thousands of years. Antioxidants protect the body from the harmful damage produced by free radical induced oxidative stress. The present study is the assessment of the total flavonoid contents and antioxidant potential of medicinal plants.

Keywords: 
ABTS, Total flavonoids, Medicinal plants.

Method Development and Estimation of Phenylenediamine in Gastric contents, Blood and Urine

Order of Publishing in Issue: 
3
Volume :15
Issue :1
January, 2021 - March, 2021
Page No: 
22-33
Authors: 
Muhammad Adnan Jamil[1], Muhammad Shahzad Aslam[2,*], Muhammad Abbas Sadiq[1], Muhammad Wasim[1], Cecilia Diaz Santiago[3], Osama Javed[4], Ahmed Shahid Mirza[5]
Address: 
[1]University of Veterinary and Animal Sciences, Lahore, Pakistan
Address: 
[2]School of Traditional Chinese Medicine, Xiamen University Malaysia
Address: 
[3]Centro Escolar University, School of Pharmacy, Manila, Philippines
Address: 
[4]University College of Pharmacy, University of the Punjab, Lahore, Pakistan
Address: 
[5]Department of Pharmaceutical Chemistry, Ziauddin University, Karachi, Pakistan

A method for detecting and estimating Paraphenylenediamine (PPD) in the biological samples has been developed and validated using High- Performance Liquid Chromatography (HPLC) with UV/VIS detector. The method quantitatively measured the PPD in the biological samples. The mobile phase was composed of 10: 90 (Acetonitrile: Ammonium acetate 25 Mm v/v) of pH 4.5. The isocratic separation was carried out at C18 silica gel column at 1ml/minute of flow rate. The spectrophotometric detection was carried out at 240 nm.

Keywords: 
Phenylenediamine, Pharmaceutical Science, Method development.

 
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