Antimicrobial activity of Abelmoschus moschatus leaf extracts

Order of Publishing in Issue: 
4
Volume :3
Issue :3
July, 2009
Page No: 
260 - 266,
Authors: 
Priti Maheshwari1 and Anil Kumar*
Address: 
School of Biotechnology, Devi Ahilya University, Khandwa Road, Indore Ð 452001, India.
Address: 
1 Present address: Department of Biological Sciences, University of Lethbridge, Alberta, Canada.
Email-ID: 
ak_sbt@yahoo.com

AbstractHexane, ethyl acetate, methanol andaqueous extracts prepared from the leaves ofAbelmoschus moschatus were evaluated for theirantimicrobial activity against a number ofpathogens by using disc diffusion assay method.Clear zones of inhibition were reported forStaphylococcus aureus, Bacillus megaterium,Shigella flexneri, Proteus mirabilis, Proteusvulgaris and Cornebacterium diphtheriae. Afterperforming a bioassay guided fractionation of theeight hexane fractions, it was revealed that thefraction exhibiting major antibacterial activityagainst C. diphtheriae contained terpenoid oil.

Keywords: 
Antibiotic, bioactivity guided fractionation, crude extracts, disc diffusion assay.
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